Because of changes in our gaming group's makeup, I haven't been refereeing D&D in any form for a while, but I have been playing in a Labyrinth Lord campaign that uses the excellent Red Tide setting. In that campaign, I play a cleric of the Maker named Brother Egon. In the course of the adventure, our party rescued a wounded young boy, who, upon waking up, began to cry hysterically, making it impossible for my no-nonsense cleric to interrogate him about how he came to be in his current predicament. Unable to calm the boy, Brother Egon turned to one of our female companions, a Viking-esque warrior woman named Inga Skarsgard. I implored her, "Inga, you're a woman, calm the boy." Then, my wife, who's playing Inga, said, without missing a beat, in a loud voice, "Stop crying, stupid boy!"
It was priceless.